Mechanisms of organogenesis of primary lymphoid follicles
نویسندگان
چکیده
منابع مشابه
Mechanisms of organogenesis of primary lymphoid follicles.
Primary lymphoid follicles (PLFs) in secondary lymphoid tissue (SLT) of mammals are the backbone for the formation of follicular dendritic cell (FDC) networks. These are important for germinal center reactions during which affinity maturation creates optimized antibodies in adaptive immune responses. In the context of organogenesis, molecular requirements for the formation of follicles have bee...
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Lymphoid follicles (LFs) can be induced in the lung on infection or chronic inflammation; however, their relevance and contribution to protective immunity or pathogenesis is poorly understood. Recent advances from clinical studies and animal models have shed some light on the mechanisms that trigger and facilitate the development of LFs. As we grasp a better understanding of their development a...
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ژورنال
عنوان ژورنال: International Immunology
سال: 2008
ISSN: 1460-2377,0953-8178
DOI: 10.1093/intimm/dxn020